Chemistry Major (B.S.) - Undergraduate (Combined B.S./M.S.) - 2011 University Catalog

You are viewing the 2011 University Catalog. Please see the newest version of the University Catalog for the most current version of this program's requirements.

A minimum of 120 semester hours of coursework is required for the baccalaureate degree with a minimum 2.0 overall GPA, and a minimum 2.0 major GPA. However, more than 120 semester hours may be required depending upon the major field of study. In addition to the major requirement outlined below, all university students must fulfill the set of General Education requirements applicable to their degree (for further information, see General Education Requirements).

CHEMISTRY MAJOR (Combined BS/MS)

Complete 74 semester hours including the following 5 requirement(s):

  1. REQUIRED COURSES

    Complete 40 semester hours: .

    CHEM 120 General Chemistry I 4
    CHEM 121 General Chemistry II 4
    CHEM 230 Organic Chemistry I 3
    CHEM 231 Organic Chemistry II 3
    CHEM 232 Experimental Organic Chemistry I 2
    CHEM 233 Experimental Organic Chemistry II 2
    CHEM 310 Analytical Chemistry 5
    CHEM 311 Instrumental Analysis 4
    CHEM 340 Physical Chemistry I 3
    CHEM 341 Physical Chemistry II 3
    CHEM 343 Experimental Physical Chemistry 2
    CHEM 370 Biochemistry I 3
    CHEM 495 The Chemical Literature 1
    CHEM 499 Undergraduate Research 1-3
  2. ELECTIVE COURSES

    Complete 6 semester hours from the following: .

    CHEM 410 Advanced Quantitive Analysis 4
    CHEM 420 Advanced Inorganic Chemistry 3
    CHEM 430 Advanced Organic Chemistry 3
    CHEM 440 Advanced Physical Chemistry 3
    CHEM 471 Biochemistry II 3
    CHEM 490 Selected Topics in Chemistry 2-3
  3. COLLATERAL COURSES - MATH

    Complete the following 2 requirements:

    1. Complete the following 2 courses:

      MATH 122 Calculus I 4
      MATH 221 Calculus II 4
    2. Complete 1 course from the following:

      STAT 330 Fundamentals of Modern Statistics I 3
      STAT 401 Applied Statistics for the Sciences 3
  4. COLLATERAL COURSES - PHYS

    Complete 2 courses:

    PHYS 191 University Physics I 4
    PHYS 192 University Physics II 4
  5. GRADUATE COURSES

    As part of the combined BS/MS Chemistry program, complete 9 semester hours from the following:

    CHEM 510 Hazardous Materials Management 3
    CHEM 521 Advanced Topics in Inorganic Chemistry 3
    CHEM 525 Bioinorganic Chemistry 3
    CHEM 531 Advanced Topics in Organic Chemistry 3
    CHEM 532 Organic Synthesis 3
    CHEM 533 Biosynthesis of Natural Products 3
    CHEM 534 Chromatographic Methods: Theory and Practice 3
    CHEM 536 Nuclear Magnetic Resonance: Theory and Practice 3
    CHEM 538 Drug Design in Medicinal Chemistry 3
    CHEM 540 Chemical Thermodynamics 3
    CHEM 542 Theoretical Physical Chemistry 3
    CHEM 544 Electrochemistry 3
    CHEM 546 Chemical Spectroscopy 3
    CHEM 548 Chemical Kinetics 3
    CHEM 550 Organometallic Chemistry 3
    CHEM 570 Selected Topics in Advanced Biochemistry 3
    CHEM 574 Protein Structure 3
    CHEM 575 Enzyme Kinetics and Mechanisms 3
    CHEM 576 Lipid Biochemistry 3
    CHEM 577 Nucleic Acid Biochemistry 3
    CHEM 578 Biochemistry Laboratory Techniques 3
    CHEM 579 Biomolecular Assay Development 3
    CHEM 582 Biochemical Pharmacology 3
    CHEM 590 Selected Topics-Advanced Chemistry 3
    CHEM 595 Graduate Research 1-3
    CHEM 599 Graduate Literature Search in Chemistry 2

Course Descriptions:

CHEM120: General Chemistry I

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to atomic and molecular structure, bonding, stoichiometry, states of matter, solutions, and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. (3 hours lecture, 3 hours lab.) 4 sh.

Prerequisites: One year of high school chemistry.

CHEM121: General Chemistry II

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to thermochemistry, kinetics; general acid base, precipitation, redox equilibria, electrochemistry and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. (3 hours lecture, 3 hours lab.) 4 sh.

Prerequisites: CHEM 120 with a grade of C- or better.

CHEM230: Organic Chemistry I

Structure and bonding in organic compounds: nomenclature, reactions, properties, and aromatic compounds: stereochemistry; structure analysis by IR, NMR, UV, and MS; introduction to molecular orbital theory. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 121 with a grade of C- or better.

CHEM231: Organic Chemistry II

Nomenclature, reactions, properties, and synthesis of ethers, epoxides, alcohols, amines, and carbonyl compounds; carbohydrates; amino acids, peptides and proteins; pericyclic reactions; synthetic polymers. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 230 with a grade of C- or better.

CHEM232: Experimental Organic Chemistry I

A laboratory course to be taken concurrently with CHEM 230. Basic techniques for the separation, analysis and synthesis of organic compounds: recrystallization, distillation, extraction, GC, HPLC, TLC, GC/MS, IR, H/C13- NMR, chemical safety methods and regulations. (4 hours lab.) 2 sh.

Prerequisites: CHEM 230 is a prerequisite or corequisite.

CHEM233: Experimental Organic Chemistry II

A laboratory course to be taken concurrently with CHEM 231 and after completion of CHEM 232. Basic techniques for organic synthesis, mechanistic studies, separation and analysis, and chemical safety: multistep syntheses, spectral data-base searching, phase-transfer catalysis, anhydrous procedures, analysis of unknowns by wet-chemical and spectral methods. (4 hours lab.) 2 sh.

Prerequisites: CHEM 231 and 232 with a grade of C- or better. CHEM 231 may be taken as a corequisite.

CHEM310: Analytical Chemistry

Introduction to concepts of classical analytical chemistry including evaluation of data and apparatus, theory and application of volumetric and gravimetric methods and redox equilibrium, and introduction to electrical methods. (3 hours lecture, 4 hours lab.) 5 sh.

Prerequisites: CHEM 231 and CHEM 232 with a grade of C- or better.

CHEM311: Instrumental Analysis

Introduction to application of instrumental methods of analytical chemistry. Instrument techniques studied will include spectrophotometry, electroanalytical chemistry,chromatography, nuclear magnetic resonance and mass spectrometry. Theory and application will be examined in lecture and laboratory. (2 hours lecture, 6 hours lab.) 4 sh.

Prerequisites: CHEM 310 and CHEM 340 with a grade of C- or better in both courses.

CHEM340: Physical Chemistry I

Thermodynamics, homogeneous and heterogeneous equilibria, gases, electrochemistry, solutions, colligative properties. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 231, and PHYS 192, and MATH 221.

CHEM341: Physical Chemistry II

Kinetics, photochemistry, molecular physical chemistry. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 340 with a grade of C- or better.

CHEM343: Experimental Physical Chemistry

A laboratory course to be taken concurrently with CHEM 341. Application and experience with experimental techniques of physical chemistry. Students will perform experiments in calorimetry, measurement of thermodynamic variables, electro-chemical phenomena and kinetics. Analysis of experimental data, statistics and applications of microcomputers will be included. Meets the University Writing Requirement for majors in Chemistry. (4 hours lab.) 2 sh.

Prerequisites: CHEM 340 with a grade of C- or better.

CHEM370: Biochemistry I

Organization of the living cell; structure, function and chemistry of proteins, carbohydrates and lipids; bioenergetics and oxidation. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 231 with a grade of C- or better.

CHEM410: Advanced Quantitive Analysis

Extends methods of analysis in CHEM 311. Absorption and emission spectroscopy, photometry, NMR, ESR, GC, thermoanalysis, polarography, amperometry and principles of automatic analysis. (2 hours lecture, 4 hours lab.) 4 sh.

Prerequisites: CHEM 311 and CHEM 341 with a grade of C- or better in both courses.

CHEM420: Advanced Inorganic Chemistry

Physical basis of bonding and reactivity of inorganic compounds. Electronic structure of atoms, ionic and covalent bonding, symmetry properties, chemistry and structure of transition metal compounds, organometallic chemistry, introduction to solid-state structures. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 340 is a prerequisite or corequisite.

CHEM430: Advanced Organic Chemistry

Consideration of structural and electronic theories which form the basis of organic chemistry. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 340 or 370.

CHEM440: Advanced Physical Chemistry

Quantum mechanics, bonding theory, atomic structure, statistical thermodynamical calculations. (3 hours lecture.) 3 sh.

Prerequisites: MATH 420 and CHEM 341.

CHEM471: Biochemistry II

The second semester of a two semester course in biochemistry. The course continues the coverage of the chemistry of proteins, carbohydrates, lipids, and nucleic acids, and their role in cellular function and processes. Topics such as the chemistry of hormones, recombinat DNA, mechanisms of enzyme action, protein synthesis, immunoglobulins and membranes are included. Offered as CHEM 471 through Spring 2011. To become CHEM 371 effective Summer 2011. (3 hours lecture.) 3 sh.

Prerequisites: CHEM370.

CHEM490: Selected Topics in Chemistry

In-depth study of a modern aspect of chemistry. May be repeated once for a maximum of 6.0 credits as long as the topic is different. () 2 - 3 sh.

Prerequisites: CHEM 340 or 370.

CHEM495: The Chemical Literature

Introduction to web-based searching of the chemical and biochemical literature databases, including Scifinder Sholar, Science Citation Index, Science Direct, and ACS Search. Course requirements include a literature search paper and a brief seminar. Meets the University Writing Requirement for majors in Chemistry. (3 hours lab.) 1 sh.

Prerequisites: CHEM 370 or CHEM 340 may be taken as prerequisite or corequisite.

CHEM499: Undergraduate Research

Laboratory research on a specific problem in chemistry under guidance of a faculty mentor. () 1 - 3 sh.

Prerequisites: CHEM 233, Experimental Chemistry II, and departmental approval.

CHEM510: Hazardous Materials Management

Exploration of the physical and chemical characteristics of hazardous chemicals, hazardous waste, and mixed waste materials. Their sources, handling, transportation, storage, disposal, and regulation. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 230 or equivalent. For majors in College of Sciences and Mathematics or instructor's permission.

CHEM521: Advanced Topics in Inorganic Chemistry

Current theories of inorganic structure, reactions and properties. May be repeated twice for a maximum of 9.0 credits as long as the topic is different. (3 hours lecture.) 3 sh.

Prerequisites: One year of physical chemistry.

CHEM525: Bioinorganic Chemistry

Exploration of the vital roles that metal atoms play in biochemical processes. Transition metal interactions with proteins will be emphasized. The course will focus on the structural, regulatory, catalytic, transport, and oxidation-reduction functions of metal containing biomolecules. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM531: Advanced Topics in Organic Chemistry

Modern theories of organic chemistry with emphasis on electronic theory and reaction mechanisms. May be repeated three times for a maximum of 12.0 credits as long as the topic is different. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 430 (Advanced Organic Chemistry).

CHEM532: Organic Synthesis

Detailed study of the art, methods, and the philosophy of organic synthesis beginning with a review of classical and modern synthetic methods, followed by the planning theory of synthesis and culminating in a study of elegant syntheses in the literature. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 430 (Advanced Organic Chemistry).

CHEM533: Biosynthesis of Natural Products

A study of natural products with emphasis on the biosynthesis of primary and secondary metabolites. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 430 (Advanced Organic Chemistry) or equivalent.

CHEM534: Chromatographic Methods: Theory and Practice

A combined lecture/hands-on course in the theory and practice of chromatography; including GC, HPLC, GC-MS, GPC, and SFC, as well as computerized instrument control, data acquistion, and processing. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 310 (Analytical Chemistry) and 311 (Instrumental Analysis) or equivalents.

CHEM536: Nuclear Magnetic Resonance: Theory and Practice

A combination lecture/hands-on course utilizing the department's FT-NMR's to provide students with theoretical background and practical experience in modern 1-D and 2-D FT-NMR. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 310 (Analytical Chemistry) and 311 (Instrumental Analysis) or equivalents.

CHEM538: Drug Design in Medicinal Chemistry

A comprehensive course covering the design and action of pharmaceutical agents. (3 hours lecture.) 3 sh.

Prerequisites: Matriculation into the graduate program or permission of instructor.

CHEM540: Chemical Thermodynamics

In-depth study of classical thermodynamics. Development of thermodynamic functions describing chemical systems in equilibrium, with emphasis on systems of variable composition. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM542: Theoretical Physical Chemistry

Theoretical development of quantum mechanics and statistical mechanics as applied to chemistry. Application of theoretical procedures to atomic and molecular structure and bonding. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) and MATH 420 (Differential Equations).

CHEM544: Electrochemistry

Principles and application of electrochemistry, relationship of electrochemical principles to classical thermodynamics, and practical applications of electrochemistry. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II).

CHEM546: Chemical Spectroscopy

Introduction to the theory of molecular spectroscopy. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II).

CHEM548: Chemical Kinetics

Kinetics in its role of elucidating reaction mechanisms. Discussion of recent problems from the chemical literature including fast reactions and enzyme kinetics. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II).

CHEM550: Organometallic Chemistry

The course will introduce students to organometallic chemistry, mainly involving transition metals, but also including some main group metals. The material covered will focus on the unique chemistry of these compounds and their uses in organic synthesis, material science, and as catalysts. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 420 and CHEM 430 or equivalents.

CHEM570: Selected Topics in Advanced Biochemistry

A detailed treatment of selected topics in biochemistry. Special emphasis upon recent developments. Protein structure, enzymology, metabolism, nucleic acid chemistry are examples of topics. This course may be repeated for credit indefinitely as long as the topic is different each time. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 370 or instructor's permission.

CHEM574: Protein Structure

Primary, secondary and tertiary structure of proteins, protein structural motifs and protein structural families. Globular proteins, DNA binding proteins, membrane proteins, signal transduction systems, immune system protein structure, methods used for determination of protein structure. (3 hours lecture.) 3 sh.

Prerequisites: One semester of introductory Biochemistry or similar background.

CHEM575: Enzyme Kinetics and Mechanisms

The following properties of enzymes are considered: structure, specificity, catalytic power, mechanism of action, multienzyme complexes, kinetics, regulation, and multienzyme systems. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM576: Lipid Biochemistry

Chemistry of plant and animal lipids, their occurrence, metabolism, and industrial uses. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM577: Nucleic Acid Biochemistry

This course will present fundamental aspects of nucleic acid biochemistry including structure and biological function and will be organized according to a systematic consideration of techniques used in the study of nucleic acids. Current literature and key topics such as protein-DNA, protein-drug complexes and nucleic acid repair mechanisms will be considered. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM578: Biochemistry Laboratory Techniques

Fundamental techniques used to isolate, characterize, and study nucleic acids, proteins, carbohydrates, and lipids. Theory and application of buffers, spectrophotometry, tissue fractionation, centrifugation, extraction, chromatographic separations, electrophoresis, radioactivity, enzyme purification and dinetics, enzymatic assays, NMR and MS structure determination. (2 hours lecture, 3 hours lab.) 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM579: Biomolecular Assay Development

This course will provide the student with hands-on experience of state of the art techniques used for drug discovery research in the pharmaceutical industry. These techniques include assay development for high throughput screening and molecular docking methods for lead discovery. Using these techniques will allow the student to understand the drug discovery process, which includes a dialogue between crystallographers, medicinal chemists, biochemists, and biologists. (2 hours lecture, 3 hours lab.) 3 sh.

Prerequisites: CHEM 370 or instructor's permission.

CHEM582: Biochemical Pharmacology

How drugs interact with, and influence biochemical pathways relevant to disease in the whole organism. Topics covered in this course deal with a review of fundamental concepts in biochemisty relevant to drug discovery, the process of drug discovery and specific examples of drug interactions with biochemical pathways and how they impact human disease. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 370 and CHEM 371.

CHEM590: Selected Topics-Advanced Chemistry

An in-depth study of selected areas in either analytical, inorganic, organic or physical chemistry, with special emphasis upon recent developments in the field. May be repeated three times for a maximum of 12 credits as long as the topic is different each time. (3 hours lecture.) 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM595: Graduate Research

Directed individual laboratory investigation under guidance of faculty advisor. May be elected once or twice, maximum credit allowed is 3 semester hours. () 1 - 3 sh.

Prerequisites: Completion of 12 semester hours in this graduate program; instructor's permission.

CHEM599: Graduate Literature Search in Chemistry

An individual, non-experimental investigation utilizing the scientific literature. () 2 sh.

Prerequisites: Completion of 12 semester hours in this graduate program.

MATH122: Calculus I

Limits, continuity; derivative and differentiation; applications of the derivative, maxima, minima, and extreme considerations; antiderivatives; Riemann integral. (4 hours lecture.) 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Readiness Test.)

MATH221: Calculus II

Riemann integral applications, transcendental functions, techniques of integration, improper integrals, L'Hospital's rule, infinite series. (4 hours lecture.) 4 sh.

Prerequisites: MATH 122.

PHYS191: University Physics I

This one-semester calculus-based course including laboratory is a study of the principles of physics and some applications to society's problems. Topics covered include mechanics, thermodynamics, fluids, and harmonic motion. (3 hours lecture, 2 hours lab.) 4 sh.

Prerequisites: MATH 122 is prerequisite or co-requisite.

PHYS192: University Physics II

Calculus-based course. Study of some principles of physics and some applications to society's problems. Topics include: wave motion, sound and noise pollution, optics, electricity, lasers, nuclear theory, radiation, nuclear reactors, waste disposal. (3 hours lecture, 2 hours lab.) 4 sh.

Prerequisites: MATH 221 is prerequisite or corequisite.

STAT330: Fundamentals of Modern Statistics I

Displaying, describing and modeling data; arrangements for producting data; probability; methods for drawing conclusions from data: significance testing, confidence interval estimation, linear regression, analysis of variance. Examples from many disciplines including the social and natural sciences. Statistical software is used. (3 hours lecture.) 3 sh.

Prerequisites: MATH 221.

STAT401: Applied Statistics for the Sciences

Organizing, displaying, and describing data; designing experiments; methods for drawing conclusions from data; significance testing, confidence intervals, linear regression, analysis of variance, chi-square tests of independence. Examples from disciplines in the natural and physical sciences. Statistical software is used. Not for Mathematics and Computer Science majors. (3 hours lecture.) 3 sh.

Prerequisites: MATH 111 or Math 112.