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Computational Fluid Dynamics of Cerebral Aneurysms

January 29, 2018, 11:00 am - 12:00 pm
Location Center for Environmental and Life Sciences - 207
Posted InCollege of Science and Mathematics
Mathematical Scienceshttp://www.montclair.edu/mathematical-sciences/TypeDepartment Seminar

Dr. Bong Jae Chung, George Mason University, presents their seminar.

About the Seminar

It is widely known that the rupture of intracranial aneurysms has devastating consequences with large morbidity and mortality rates. The etiology of aneurysms has been discussed earlier by many scientists and clinicians. It is now well accepted that hemodynamic environments in aneurysms play a key role in initiation, growth, and rupture processes in combination with biochemical and physical interactions. Computational fluid dynamics (CFD) using patient specific aneurysm images from 3DRA or CTA has been used for several years to identify mechanical risk factors such as wall shear stress (WSS). The flow features are believed to be associated with aneurysm evolution and rupture. We also need to understand flow characteristics before and after surgical treatments such as coils and stent in order to help the clinical decision making process. In order to tackle the problem, we need to solve Navier-Stokes Equations in complex 3D patient specific geometries. High level of accuracy and computational cost are required to obtain valuable computational results to help clinicians. Finite Element Method is used along with Immersed Boundary technique to study flow features before and after treatment. Mechanical quantities from flow fields such as pressure and oscillatory shear index are identified as biomarkers. In this talk, I present a computational study of hemodynamics in the aneurysms of eight patients. I also present hemodynamic analysis of aneurysm occlusion by stent.