Molecular Biology Major (B.S.) - Undergraduate - 2009 University Catalog

You are viewing the 2009 University Catalog. Please see the newest version of the University Catalog for the most current version of this program's requirements.

The main objectives of our undergraduate Molecular Biology major are: to educate students in greater depth in molecular studies than would be possible in our Biology program, and to prepare students in the methodological advances which have changed the study of biology in recent years.  The field of molecular biology has an impact on almost every other area of study in the biological sciences, and its development has led to expanded graduate and professional programs.  The Molecular Biology curriculum will provide undergraduate students with a fundamental knowledge of the principles and practices inherent in the rapidly advancing field of molecular biology.

Students who major in Molecular Biology can also enter the burgeoning biotechnology industry, well prepared to compete in the modern scientific marketplace, as most institutions carry on basic or applied research in biomedical areas today using techniques of molecular biology.  Students completing this major will be well-prepared to enter professional schools of medicine, dentistry, veterinary medicine, and optometry, as well as graduate programs.


MOLECULAR BIOLOGY MAJOR

Complete 78 semester hours including the following 6 requirement(s):

  1. MOLECULAR BIOLOGY REQUIRED COURSES

    Complete the following 2 requirement(s) for 30 semester hours:

    1. Complete the following 7 courses for 26 semester hours:

      BIOL 112 Principles of Biology I 4
      BIOL 113 Principles of Biology II 4
      BIOL 230 Cell and Molecular Biology 4
      BIOL 350 Microbiology 4
      BIOL 380 Genetics 4
      BIOL 434 Introductory Molecular Biology 3
      BIOL 435 Experimental Molecular Biology 3
    2. Complete 4 semester hours from the following:

      BIOL 409 Externship in Biological Research (Co-operative Education) 1-4
      BIOL 418 Biology Independent Research 1-4
  2. MOLECULAR BIOLOGY ELECTIVE COURSES

    Complete 8 semester hours from the following:

    BICL 405 Cell Culture 3
    BICL 406 Scanning Electron Microscopy 4
    BIOL 409 Externship in Biological Research (Co-operative Education) 1-4
    BIOL 411 Introduction to Transmission Electron Microscopy 4
    BIOL 418 Biology Independent Research 1-4
    BIOL 425 Elementary Plant Physiology 3
    BIOL 442 Human Physiology 4
    BIOL 443 Vertebrate Embryology 4
    BIOL 444 Cell Physiology 3
    BIOL 445 Immunology 3
    BIOL 446 Endocrinology 3
    BIOL 447 Fundamentals of Pharmacology 3
    BIOL 450 Medical Microbiology 3
    BIOL 471 Biomedical Ethics 2
    BIOL 476 Biology of Cancer 3
    BIOL 492 Senior Colloquium 1
  3. MOLECULAR BIOLOGY CHEMISTRY COLLATERAL

    Complete the following 7 courses for 22 semester hours:

    CHEM 120 General Chemistry I 4
    CHEM 121 General Chemistry II 4
    CHEM 230 Organic Chemistry I 3
    CHEM 231 Organic Chemistry II 3
    CHEM 232 Experimental Organic Chemistry I 2
    CHEM 370 Biochemistry I 3
    CHEM 471 Biochemistry II 3
  4. MOLECULAR BIOLOGY PHYSICS COLLATERAL

    Complete 1 requirement from the following for 8 semester hours:

    1. Complete the following 2 courses:

      PHYS 191 University Physics I 4
      PHYS 192 University Physics II 4
    2. Complete the following 2 courses:

      PHYS 193 College Physics I 4
      PHYS 194 College Physics II 4
  5. MOLECULAR BIOLOGY MATH COLLATERAL

    Complete 1 requirement from the following:

    1. Complete the following 2 courses:

      MATH 109 Statistics 3
      MATH 116 Calculus A 4
    2. Complete the following 2 courses:

      MATH 122 Calculus I 4
      MATH 221 Calculus II 4
  6. MOLECULAR BIOLOGY COLLATERALS

    Complete 3 semester hours from the following:

    CMPT 109 Introduction to Computer Applications: Being Fluent with Information Technology 3
    CMPT 183 Foundations of Computer Science I 3

Course Descriptions:

BICL405: Cell Culture

Theory of and practice in working with living cells: tissue culture techniques, cell communication, differentiation, regeneration and aging in several living cell systems. 3 sh.

Prerequisites: Departmental approval.

BICL406: Scanning Electron Microscopy

Introduction to theory and practice of scanning electron microscopy. Includes specimen preparation, scanning electron microscope operation, electron specimen interactions/imagery, and microanalysis. 4 sh.

Prerequisites: Departmental approval.

BIOL112: Principles of Biology I

Principles of Biology I involves the study of life from molecule to multicellular organism with focus on structure and function of cells, mechanisms of heredity and change, and the ways in which these processes shape higher levels of biological organization. This course is designed to fulfill the first core course requirement of the biology major. 4 sh.

Prerequisites: For incoming freshmen Spring 2007 and before, BIOL 100 or minimum MSUPT composite score of 160 for writing and reading. For incoming freshmen as of Fall 2007 and thereafter, Basic Skills Reading Test of >61 AND Basic Skills Math Test (arithmetic) of >74 OR grade of "C" or better in BIOL 100.

BIOL113: Principles of Biology II

Principles of Biology II will provide an introductory level study of biodiversity and the origins of life, phylogenetic relationships among organisms, genetics, developmental biology, reproduction, the biology of populations and communities, and ecosystem processes. Meets Gen Ed 2002 - Interdisciplinary Core, Scientific Issues. 4 sh.

Prerequisites: For incoming freshmen Spring 2007 and before, BIOL 100 or minimum MSUPT composite score of 160 for writing and reading. For incoming freshmen as of Fall 2007 and thereafter, Basic Skills Reading Test of >61 AND Basic Skills Math Test (arithmetic) of >74 OR grade of "C" or better in BIOL 100.

BIOL230: Cell and Molecular Biology

An introduction to the chemistry, structure, and function of prokaryotic and eukaryotic cells. Topics covered include membrane structure and transport processes, bioenergetics and energy transformations in cells, DNA replication and expression, protein synthesis, and cell movement. 4 sh.

Prerequisites: CHEM 120 with a grade of "C-" or better.

BIOL350: Microbiology

A study of bacteria, yeast, molds and other microorganisms in relation to modern biological concepts and the welfare of man. Standard techniques employed in the laboratory. 4 sh.

Prerequisites: BIOL 230 and CHEM 120.

BIOL380: Genetics

Lecture and lab. Heredity, gene and chromosomal structure and function, gene regulation, mutation and repair, genes in populations, genetic manipulation, and applied genetics are covered. Lab exercises demonstrate genetic concepts. A semester-long project with research paper is required. Required of all biology majors and minors. Meets the University Writing Requirement for BDPT, BIBM, BICM, BIDE, BIED, BIES, BIME, BIOL, BMPA, MBDP, MOBI, SIBC, SICS and SIMB majors. 4 sh.

Prerequisites: BIOL 230 with a grade of "C-" or better and CHEM 120.

BIOL409: Externship in Biological Research (Co-operative Education)

Full or part-time work in an established laboratory with a scientific investigator for the duration of the term. 1 - 4 sh.

Prerequisites: Departmental approval.

BIOL411: Introduction to Transmission Electron Microscopy

Basic theory and practice of electron microscopy. Specimen preparation, ultramicrotomy, microscopy, photographic preparation of final print, interpretation of results. 4 sh.

Prerequisites: BIOL 230.

BIOL418: Biology Independent Research

Under the guidance of a sponsor, students will investigate individual problems of appropriate scope. A written and/or oral report is required. (Offered on demand.) 1 - 4 sh.

Prerequisites: Minimum GPA 3.0 and departmental approval.

BIOL425: Elementary Plant Physiology

Major physiological processes of the flowering plant: growth, metabolism, photosynthesis, respiration, water relations and mineral nutrition. (Not offered every year.) 3 sh.

Prerequisites: BIOL 113 and BIOL 230 and CHEM 230 or permission of instructor.

BIOL434: Introductory Molecular Biology

This course is designed to examine the molecular biology of plant and animal cells. 3 sh.

Prerequisites: BIOL 350, and 380, and CHEM 370.

BIOL435: Experimental Molecular Biology

A laboratory course that will introduce biology and molecular biology majors to the basic techniques of modern molecular biology. Techniques to be covered include nucleic acid isolation, restriction enzyme mapping, plasmid manipulation and subcloning, genomic library construction, PCR amplification, and DNA sequence analysis. 3 sh.

Prerequisites: BIOL 434.

BIOL442: Human Physiology

Functions of animal organs and systems with emphasis on maintenance of homeostasis. 4 sh.

Prerequisites: BIOL 113 (or BIOL 132 if completed prior to Fall 2002), and BIOL 230 with a grade of "C-" or better, and CHEM 230.

BIOL443: Vertebrate Embryology

Developmental anatomy of the vertebrates, especially amphibian, chick and human. General concepts of development and cell differentiation. (Not offered every year.) 4 sh.

Prerequisites: BIOL 113 (or BIOL 132 if completed prior to Fall 2002) and BIOL 230.

BIOL444: Cell Physiology

Advanced course in cell function. 3 sh.

Prerequisites: BIOL 230 with a grade of "C-" or better, and CHEM 230.

BIOL445: Immunology

Cellular and humoral immunal responses, immunoglobulins, antigen-antibody reactions, immunopathology, transplantation and blood transfusion. (Not offered every year.) 3 sh.

Prerequisites: BIOL 230 with a grade of "C-" or better, and CHEM 230.

BIOL446: Endocrinology

Basic anatomy and physiology of the mammalian endocrine glands with special attention directed to the human endocrine glands. The interrelationships between the various endocrines including neural control and the role of these glands in maintaining the homeostasis of the body will be stressed. 3 sh.

Prerequisites: BIOL 230 with a grade of "C-" or better, and CHEM 230.

BIOL447: Fundamentals of Pharmacology

Introduction to the study of chemicals that have biological effects, with special emphasis on those with medical importance. 3 sh.

Prerequisites: BIOL 230 and CHEM 230.

BIOL450: Medical Microbiology

The course is designed to acquaint the biology major with those microorganisms which cause disease, the prevention of disease, therapeutic agents to control microbial diseases and the body's natural defense mechanisms. 3 sh.

Prerequisites: BIOL 350.

BIOL471: Biomedical Ethics

Seminar course dealing with ethical dilemmas posed by advances in biomedical technology. Background readings in ethics will be followed by discussions of readings on the applications and consequences of modern biomedical research. 2 sh.

Prerequisites: BIOL 380.

BIOL476: Biology of Cancer

An in depth examination of the biology of cancer, including risk factors, genetics, causes of cancer, metastasis, therapies (conventional and recombinant DNA), and prevention will be presented. This course will also help students develop proficiency in critically evaluating primary scientific articles dealing with cancer. 3 sh.

Prerequisites: BIOL 230, BIOL 380, and CHEM 231.

BIOL492: Senior Colloquium

Students in this course will read primary resources material and interpret the data. This course will also teach students how to read, critique and present scientific data to a peer group. Students will analyze, discuss and present primary research articles with respect to scientific content, accuracy of the data and significance of the experiments. 1 sh.

Prerequisites: BIOL 230 or departmental approval.

CHEM120: General Chemistry I

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to atomic and molecular structure, bonding, stoichiometry, states of matter, solutions, and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. Meets the 1983 General Education Requirement (GER) - Natural/Physical Science, Laboratory or Non-Laboratory Science. 4 sh.

Prerequisites: One year of high school chemistry.

CHEM121: General Chemistry II

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to thermochemistry, kinetics; general acid base, precipitation, redox equilibria, electrochemistry and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. 4 sh.

Prerequisites: CHEM 120.

CHEM230: Organic Chemistry I

Structure and bonding in organic compounds: nomenclature, reactions, properties, and aromatic compounds: stereochemistry; structure analysis by IR, NMR, UV, and MS; introduction to molecular orbital theory. 3 sh.

Prerequisites: CHEM 121.

CHEM231: Organic Chemistry II

Nomenclature, reactions, properties, and synthesis of ethers, epoxides, alcohols, amines, and carbonyl compounds; carbohydrates; amino acids, peptides and proteins; pericyclic reactions; synthetic polymers. 3 sh.

Prerequisites: CHEM 230.

CHEM232: Experimental Organic Chemistry I

A laboratory course to be taken concurrently with CHEM 230. Basic techniques for the separation, analysis and synthesis of organic compounds: recrystallization, distillation, extraction, GC, HPLC, TLC, GC/MS, IR, H/C13- NMR, chemical safety methods and regulations. 2 sh.

Prerequisites: CHEM 230 is a prerequisite or corequisite.

CHEM370: Biochemistry I

Organization of the living cell; structure, function and chemistry of proteins, carbohydrates and lipids; bioenergetics and oxidation.. 3 sh.

Prerequisites: CHEM 231.

CHEM471: Biochemistry II

The second semester of a two semester course in biochemistry. The course continues the coverage of the chemistry of proteins, carbohydrates, lipids, and nucleic acids, and their role in cellular function and processes. Topics such as the chemistry of hormones, recombinat DNA, mechanisms of enzyme action, protein synthesis, immunoglobulins and membranes are included. 3 sh.

Prerequisites: CHEM370.

CMPT109: Introduction to Computer Applications: Being Fluent with Information Technology

An introduction to the skills, concepts, and capabilities necessary to effectively use information technology across the curriculum through computer applications. Not for mathematics major elective credit or computer science elective credit. Meets Gen Ed 2002 - Computer Science. Meets the 1983 General Education Requirement (GER) - Mathematics, Computer Science. 3 sh.

Prerequisites: MATH 051 or MATH 061 or satisfactory score on both of the mathematical components of the MSUPT.

CMPT183: Foundations of Computer Science I

Basic theory of digital computers. Syntax and semantics of a programming language. Algorithms: logic, design, testing and documentation. Meets the 1983 General Education Requirement (GER) - Mathematics, Computer Science. 3 sh.

Prerequisites: MATH 100, MATH 112, MATH 114, MATH 116, MATH 122 or MATH 221.

MATH109: Statistics

Introduction to the use of statistics in the real world. Topics include: analysis and presentation of data, variability and uncertainty in data, techniques of statistical inference and decision-making. Meets Gen Ed 2002 - Mathematics. Meets the 1983 General Education Requirement (GER) - Mathematics, Mathematics. 3 sh.

Prerequisites: MATH 051 or MATH 061 or placement through the Montclair State University Placement Test (MSUPT). Not for majors in Mathematics (MATH), Mathematics with Applied Math concentration (MAAM) or Mathematics-Teacher Education (MTED).

MATH116: Calculus A

Differentiation and integration of functions, including trigonometric functions. Applications to biology and geoscience. Meets the 1983 General Education Requirement (GER) - Mathematics, Mathematics. 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Rediness Test.)

MATH122: Calculus I

Limits, continuity; derivative and differentiation; applications of the derivative, maxima, minima, and extreme considerations; antiderivatives; Riemann integral. Meets the 1983 General Education Requirement (GER) - Mathematics, Mathematics. 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Readiness Test.)

MATH221: Calculus II

Riemann integral applications, transcendental functions, techniques of integration, improper integrals, L'Hospital's rule, infinite series. Meets the 1983 General Education Requirement (GER) - Mathematics, Mathematics. 4 sh.

Prerequisites: MATH 122.

PHYS191: University Physics I

This one-semester calculus-based course including laboratory is a study of the principles of physics and some applications to society's problems. Topics covered include mechanics, thermodynamics, fluids, and harmonic motion. Meets the 1983 General Education Requirement (GER) - Natural/Physical Science, Laboratory or Non-Laboratory Science. 4 sh.

Prerequisites: MATH 122 is prerequisite or co-requisite.

PHYS192: University Physics II

Calculus-based course. Study of some principles of physics and some applications to society's problems. Topics include: wave motion, sound and noise pollution, optics, electricity, lasers, nuclear theory, radiation, nuclear reactors, waste disposal. Meets the 1983 General Education Requirement (GER) - Natural/Physical Science, Laboratory or Non-Laboratory Science. 4 sh.

Prerequisites: MATH 221 is prerequisite or corequisite.

PHYS193: College Physics I

This one-semester course including laboratory is a study of the principles and applications of classical physics. Topics covered include mechanics, heat and thermodynamics, wave motion and sound, as well as societal applications of physical principles. Calculus is not used, but familiarity with some algebra and trigonometry is required. Meets the 1983 General Education Requirement (GER) - Natural/Physical Science, Laboratory or Non-Laboratory Science. 4 sh.

Prerequisites: MATH 100.

PHYS194: College Physics II

This one-semester course including laboratory is a study of the principles and applications of classical physics. Topics covered include optics, electricity and magnetism, and an introduction to modern and nuclear physics, as well as societal applications of physical principles. Calculus is not used, but familiarity with some algebra and trigonometry is required. Meets the 1983 General Education Requirement (GER) - Natural/Physical Science, Laboratory or Non-Laboratory Science. 4 sh.

Prerequisites: MATH 100, or MATH 111, or MATH 112, or PHYS 193.