Chemistry Major (B.S.) - Undergraduate (Combined B.S./M.S.) - 2015 University Catalog

A minimum of 138 semester hours of coursework is required for the combined BS/MS degree; 112 semester hours from the undergraduate program and 26 semester hours from the graduate program. In addition, a minimum 3.0 major GPA is required at the end of the junior year.  Students should have taken at least three 300 level chemistry courses, including CHEM 341 at Montclair State University.  The Graduate Record Examination (GRE) is not required.  Students who have completed a BS in Chemistry are not eligible for this program.  Students who complete the program will be awarded both degrees at the end of five years. The undergraduate component includes all requirements for certification of the BS degree by the American Chemical Society Committee on Professional Training.  The BS/MS program has more chemistry, mathematics and research requirements than the BS and MS degrees separately.  If pursued independently, these two degrees would require a total of 152 semester hours and would take six years to complete.  A student who decides not to complete the program can graduate with a BS degree by completing the requirements for the BS in Chemistry.

In addition to the program requirements outlined below, all university students must fulfill the set of General Education requirements applicable to their degree.


CHEMISTRY MAJOR (Combined BS/MS)

Complete 74 semester hours including the following 5 requirement(s):

  1. REQUIRED COURSES

    Complete 40 semester hours: .

    CHEM 120 General Chemistry I (3 hours lecture, 3 hours lab) 4
    CHEM 121 General Chemistry II (3 hours lecture, 3 hours lab) 4
    CHEM 230 Organic Chemistry I (3 hours lecture) 3
    CHEM 231 Organic Chemistry II (3 hours lecture) 3
    CHEM 232 Experimental Organic Chemistry I (4 hours lab) 2
    CHEM 233 Experimental Organic Chemistry II (4 hours lab) 2
    CHEM 310 Analytical Chemistry (3 hours lecture, 4 hours lab) 5
    CHEM 311 Instrumental Analysis (2 hours lecture, 6 hours lab) 4
    CHEM 340 Physical Chemistry I (3 hours lecture) 3
    CHEM 341 Physical Chemistry II (3 hours lecture) 3
    CHEM 343 Experimental Physical Chemistry (4 hours lab) 2
    CHEM 370 Biochemistry I (3 hours lecture) 3
    CHEM 495 The Chemical Literature (3 hours lab) 1
    CHEM 499 Undergraduate Research 1-3
  2. ELECTIVE COURSES

    Complete 6 semester hours from the following: .

    CHEM 371 Biochemistry II (3 hours lecture) 3
    CHEM 420 Advanced Inorganic Chemistry (3 hours lecture) 3
    CHEM 430 Advanced Organic Chemistry (3 hours lecture) 3
    CHEM 440 Advanced Physical Chemistry (3 hours lecture) 3
    CHEM 490 Selected Topics in Chemistry 2-3
  3. COLLATERAL COURSES - MATH

    Complete the following 2 requirements:

    1. Complete the following 2 courses:

      MATH 122 Calculus I (4 hours lecture) 4
      MATH 221 Calculus II (4 hours lecture) 4
    2. Complete 1 course from the following:

      STAT 330 Fundamentals of Modern Statistics I (3 hours lecture) 3
      STAT 401 Applied Statistics for the Sciences (3 hours lecture) 3
  4. COLLATERAL COURSES - PHYS

    Complete 2 courses:

    PHYS 191 University Physics I (3 hours lecture, 2 hours lab) 4
    PHYS 192 University Physics II (3 hours lecture, 2 hours lab) 4
  5. GRADUATE COURSES

    As part of the combined BS/MS Chemistry program, complete 9 semester hours from the following:

    CHEM 510 Hazardous Materials Management (3 hours lecture) 3
    CHEM 520 Advanced Inorganic Chemistry (3 hours lecture) 3
    CHEM 525 Bioinorganic Chemistry (3 hours lecture) 3
    CHEM 530 Advanced Organic Chemistry (3 hours lecture) 3
    CHEM 532 Organic Synthesis (3 hours lecture) 3
    CHEM 533 Biosynthesis of Natural Products (3 hours lecture) 3
    CHEM 534 Separation and Analysis (3 hours lecture) 3
    CHEM 536 Nuclear Magnetic Resonance: Theory and Practice (3 hours lecture) 3
    CHEM 538 Drug Design in Medicinal Chemistry (3 hours lecture) 3
    CHEM 540 Advanced Physical Chemistry (3 hours lecture) 3
    CHEM 542 Quantum Chemistry and Spectroscopy (3 hours lecture) 3
    CHEM 544 Chemical Thermodynamics and Electrochemistry (3 hours lecture) 3
    CHEM 546 Chemical Spectroscopy (3 hours lecture) 3
    CHEM 548 Chemical Kinetics (3 hours lecture) 3
    CHEM 550 Organometallic Chemistry (3 hours lecture) 3
    CHEM 570 Advanced Biochemistry (3 hours lecture) 3
    CHEM 574 Protein Structure (3 hours lecture) 3
    CHEM 575 Enzyme Kinetics and Mechanisms (3 hours lecture) 3
    CHEM 576 Lipid Biochemistry (3 hours lecture) 3
    CHEM 577 Nucleic Acid Biochemistry (3 hours lecture) 3
    CHEM 578 Biochemistry Laboratory Techniques (2 hours lecture, 3 hours lab) 3
    CHEM 579 Biomolecular Assay Development (2 hours lecture, 3 hours lab) 3
    CHEM 582 Biochemical Pharmacology (3 hours lecture) 3
    CHEM 590 Selected Topics-Advanced Chemistry (3 hours lecture) 3
    CHEM 595 Graduate Research 1-3
    CHEM 599 Graduate Seminar (1 hour lecture) 1

Course Descriptions:

CHEM120: General Chemistry I (3 hours lecture, 3 hours lab)

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to atomic and molecular structure, bonding, stoichiometry, states of matter, solutions, and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. 4 sh.

Prerequisites: Satisfactory score on the Mathematics readiness test OR a grade of C- or better in MATH 100 or MATH 111 or MATH 112 or MATH 116 or MATH 122 or MATH 221 or MATH 222 OR concurrent enrollment in MATH 100. Satisfactory score on the Chemistry readiness test OR a grade of C- or better in CHEM 105 or CHEM 106.

CHEM121: General Chemistry II (3 hours lecture, 3 hours lab)

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to thermochemistry, kinetics; general acid base, precipitation, redox equilibria, electrochemistry and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. 4 sh.

Prerequisites: CHEM 120 with a grade of C- or better.

CHEM230: Organic Chemistry I (3 hours lecture)

Structure and bonding in organic compounds: nomenclature, reactions, properties, and aromatic compounds: stereochemistry; structure analysis by IR, NMR, UV, and MS; introduction to molecular orbital theory. 3 sh.

Prerequisites: CHEM 121 with a grade of C- or better.

CHEM231: Organic Chemistry II (3 hours lecture)

Nomenclature, reactions, properties, and synthesis of ethers, epoxides, alcohols, amines, and carbonyl compounds; carbohydrates; amino acids, peptides and proteins; pericyclic reactions; synthetic polymers. 3 sh.

Prerequisites: CHEM 230 with a grade of C- or better.

CHEM232: Experimental Organic Chemistry I (4 hours lab)

A laboratory course to be taken concurrently with CHEM 230. Basic techniques for the separation, analysis and synthesis of organic compounds: recrystallization, distillation, extraction, GC, HPLC, TLC, GC/MS, IR, H/C13- NMR, chemical safety methods and regulations. 2 sh.

Prerequisites: CHEM 230 is a prerequisite or corequisite.

CHEM233: Experimental Organic Chemistry II (4 hours lab)

A laboratory course to be taken concurrently with CHEM 231 and after completion of CHEM 232. Basic techniques for organic synthesis, mechanistic studies, separation and analysis, and chemical safety: multistep syntheses, spectral data-base searching, phase-transfer catalysis, anhydrous procedures, analysis of unknowns by wet-chemical and spectral methods. 2 sh.

Prerequisites: CHEM 231 and 232 with a grade of C- or better. CHEM 231 may be taken as a corequisite.

CHEM310: Analytical Chemistry (3 hours lecture, 4 hours lab)

Introduction to concepts of classical analytical chemistry including evaluation of data and apparatus, theory and application of volumetric and gravimetric methods and redox equilibrium, and introduction to electrical methods. 5 sh.

Prerequisites: CHEM 230 with a C- or better OR concurrent enrollment in CHEM 230 OR concurrent enrollment in CHEM 220.

CHEM311: Instrumental Analysis (2 hours lecture, 6 hours lab)

Introduction to application of instrumental methods of analytical chemistry. Instrument techniques studied will include spectrophotometry, electroanalytical chemistry, chromatography, nuclear magnetic resonance and mass spectrometry. Theory and application will be examined in lecture and laboratory. 4 sh.

Prerequisites: CHEM 310 and CHEM 340 with a grade of C- or better in both courses.

CHEM340: Physical Chemistry I (3 hours lecture)

Thermodynamics, homogeneous and heterogeneous equilibria, gases, electrochemistry, solutions, colligative properties. 3 sh.

Prerequisites: CHEM 231 and PHYS 192 and MATH 221 with a grade of C- or better in all courses.

CHEM341: Physical Chemistry II (3 hours lecture)

Kinetics, photochemistry, molecular physical chemistry. 3 sh.

Prerequisites: CHEM 340 with a grade of C- or better.

CHEM343: Experimental Physical Chemistry (4 hours lab)

A laboratory course to be taken concurrently with CHEM 341. Application and experience with experimental techniques of physical chemistry. Students will perform experiments in calorimetry, measurement of thermodynamic variables, electro-chemical phenomena and kinetics. Analysis of experimental data, statistics and applications of microcomputers will be included. Meets the University Writing Requirement for majors in Chemistry. 2 sh.

Prerequisites: CHEM 340 with a grade of C- or better.

CHEM370: Biochemistry I (3 hours lecture)

Organization of the living cell; structure, function and chemistry of proteins, carbohydrates and lipids; bioenergetics and oxidation. 3 sh.

Prerequisites: CHEM 231 with a grade of C- or better.

CHEM371: Biochemistry II (3 hours lecture)

The second semester of a two semester course in biochemistry. The course continues the coverage of the chemistry of proteins, carbohydrates, lipids, and nucleic acids, and their role in cellular function and processes. Topics such as the chemistry of hormones, recombinant DNA, mechanisms of enzyme action, protein synthesis, immunoglobulins and membranes are included. 3 sh.

Prerequisites: CHEM 370 with a grade of C- or better.

CHEM420: Advanced Inorganic Chemistry (3 hours lecture)

Physical basis of bonding and reactivity of inorganic compounds. Electronic structure of atoms, ionic and covalent bonding, symmetry properties, chemistry and structure of transition metal compounds, organometallic chemistry, introduction to solid-state structures. 3 sh.

Prerequisites: CHEM 340 is a prerequisite or corequisite.

CHEM430: Advanced Organic Chemistry (3 hours lecture)

Consideration of structural and electronic theories which form the basis of organic chemistry. 3 sh.

Prerequisites: CHEM 340 or 370.

CHEM440: Advanced Physical Chemistry (3 hours lecture)

Quantum mechanics, bonding theory, atomic structure, statistical thermodynamical calculations. 3 sh.

Prerequisites: MATH 420 and CHEM 341.

CHEM490: Selected Topics in Chemistry

In-depth study of a modern aspect of chemistry. May be repeated once for a maximum of 6.0 credits as long as the topic is different. 2 - 3 sh.

Prerequisites: CHEM 340 or 370.

CHEM495: The Chemical Literature (3 hours lab)

Introduction to web-based searching of the chemical and biochemical literature databases, including Scifinder Sholar, Science Citation Index, Science Direct, and ACS Search. Course requirements include a literature search paper and a brief seminar. Meets the University Writing Requirement for majors in Chemistry. 1 sh.

Prerequisites: CHEM 340 or CHEM 370 may be taken as prerequisite or corequisite.

CHEM499: Undergraduate Research

Laboratory research on a specific problem in chemistry under guidance of a faculty mentor. 1 - 3 sh.

Prerequisites: CHEM 233, Experimental Chemistry II, and departmental approval.

CHEM510: Hazardous Materials Management (3 hours lecture)

Exploration of the physical and chemical characteristics of hazardous chemicals, hazardous waste, and mixed waste materials. Their sources, handling, transportation, storage, disposal, and regulation. 3 sh.

Prerequisites: CHEM 230 or equivalent. For majors in College of Sciences and Mathematics or instructor's permission.

CHEM520: Advanced Inorganic Chemistry (3 hours lecture)

Major topics include: Covalent, ionic and metallic bonding; molecular structure and polarity; Bronsted-Lowry, Lewis, and hard/soft acid and base theory; symmetry and group theory; periodic trends; structures, isomers, ligand field theory, spectra, and reactions of transition metal coordination compounds; bonding and reactions of organometallic compounds; and the biological and medicinal roles of metal ions. Previous course CHEM 521 effective through Spring 2014. 3 sh.

Prerequisites: CHEM 420 or departmental approval.

CHEM525: Bioinorganic Chemistry (3 hours lecture)

Exploration of the vital roles that metal atoms play in biochemical processes. Transition metal interactions with proteins will be emphasized. The course will focus on the structural, regulatory, catalytic, transport, and oxidation-reduction functions of metal containing biomolecules. 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM530: Advanced Organic Chemistry (3 hours lecture)

Structure, reactivity and mechanisms in organic chemistry: Topics include bonding, stereochemistry, aromaticity, study of reaction mechanisms and reactive intermediates, linear free energy relationships, pericyclic reactions and organic photochemistry. Previous course CHEM 531 effective through Spring 2014. 3 sh.

Prerequisites: CHEM 430 or departmental approval.

CHEM532: Organic Synthesis (3 hours lecture)

Detailed study of the art, methods, and the philosophy of organic synthesis beginning with a review of classical and modern synthetic methods, followed by the planning theory of synthesis and culminating in a study of elegant syntheses in the literature. 3 sh.

Prerequisites: CHEM 430 (Advanced Organic Chemistry).

CHEM533: Biosynthesis of Natural Products (3 hours lecture)

A study of natural products with emphasis on the biosynthesis of primary and secondary metabolites. 3 sh.

Prerequisites: CHEM 430 (Advanced Organic Chemistry) or equivalent.

CHEM534: Separation and Analysis (3 hours lecture)

Theory and practice of major chromatographic and spectroscopic methods; including GC, HPLC, GC-MS, LC-MS/MS, FTIR, DAD- UV-VIS, and NMR. 3 sh.

Prerequisites: CHEM 310 (Analytical Chemistry) and CHEM 311 (Instrumental Analysis) or equivalents.

CHEM536: Nuclear Magnetic Resonance: Theory and Practice (3 hours lecture)

A combination lecture/hands-on course utilizing the department's FT-NMR's to provide students with theoretical background and practical experience in modern 1-D and 2-D FT-NMR. 3 sh.

Prerequisites: CHEM 310 (Analytical Chemistry) and 311 (Instrumental Analysis) or equivalents.

CHEM538: Drug Design in Medicinal Chemistry (3 hours lecture)

A comprehensive course covering the design and action of pharmaceutical agents. 3 sh.

Prerequisites: Matriculation into the graduate program or permission of instructor.

CHEM540: Advanced Physical Chemistry (3 hours lecture)

In-depth covering of thermodynamic concepts such as state functions and chemical equilibrium, calorimetry, molecular interactions, activities. Introduction to quantum chemistry. 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM542: Quantum Chemistry and Spectroscopy (3 hours lecture)

Theoretical development of quantum mechanics as applied to chemistry. Application of theoretical procedure to atomic and molecular structure and bonding. Introduction to the theory of molecular spectroscopy. 3 sh.

Prerequisites: CHEM 540 or departmental approval.

CHEM544: Chemical Thermodynamics and Electrochemistry (3 hours lecture)

In-depth study of classical thermodynamics. Development of thermodynamic functions describing chemical systems in equilibrium, with emphasis on systems of variable composition. Principles and application of electrochemistry, relationship of electrochemical principles to classical thermodynamics, and practical applications of electrochemistry. 3 sh.

Prerequisites: CHEM 540 or departmental approval.

CHEM546: Chemical Spectroscopy (3 hours lecture)

Introduction to the theory of molecular spectroscopy. 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II).

CHEM548: Chemical Kinetics (3 hours lecture)

Kinetics in its role of elucidating reaction mechanisms. Discussion of recent problems from the chemical literature including fast reactions and enzyme kinetics. 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II).

CHEM550: Organometallic Chemistry (3 hours lecture)

The course will introduce students to organometallic chemistry, mainly involving transition metals, but also including some main group metals. The material covered will focus on the unique chemistry of these compounds and their uses in organic synthesis, material science, and as catalysts. 3 sh.

Prerequisites: CHEM 420 and CHEM 430 or equivalents.

CHEM570: Advanced Biochemistry (3 hours lecture)

Structure, function, and chemistry of proteins, carbohydrates, nucleic acids, and lipids. Analytical methods biochemists use to study metabolism, regulation, binding, and catalytic activity of biomolecules. 3 sh.

Prerequisites: CHEM 370 or instructor's permission.

CHEM574: Protein Structure (3 hours lecture)

Primary, secondary and tertiary structure of proteins, protein structural motifs and protein structural families. Globular proteins, DNA binding proteins, membrane proteins, signal transduction systems, immune system protein structure, methods used for determination of protein structure. 3 sh.

Prerequisites: One semester of introductory Biochemistry or similar background.

CHEM575: Enzyme Kinetics and Mechanisms (3 hours lecture)

The following properties of enzymes are considered: structure, specificity, catalytic power, mechanism of action, multienzyme complexes, kinetics, regulation, and multienzyme systems. 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM576: Lipid Biochemistry (3 hours lecture)

Chemistry of plant and animal lipids, their occurrence, metabolism, and industrial uses. 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM577: Nucleic Acid Biochemistry (3 hours lecture)

This course will present fundamental aspects of nucleic acid biochemistry including structure and biological function and will be organized according to a systematic consideration of techniques used in the study of nucleic acids. Current literature and key topics such as protein-DNA, protein-drug complexes and nucleic acid repair mechanisms will be considered. 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM578: Biochemistry Laboratory Techniques (2 hours lecture, 3 hours lab)

Fundamental techniques used to isolate, characterize, and study nucleic acids, proteins, carbohydrates, and lipids. Theory and application of buffers, spectrophotometry, tissue fractionation, centrifugation, extraction, chromatographic separations, electrophoresis, radioactivity, enzyme purification and dinetics, enzymatic assays, NMR and MS structure determination. 3 sh.

Prerequisites: CHEM 370 or equivalent.

CHEM579: Biomolecular Assay Development (2 hours lecture, 3 hours lab)

This course will provide the student with hands-on experience of state of the art techniques used for drug discovery research in the pharmaceutical industry. These techniques include assay development for high throughput screening and molecular docking methods for lead discovery. Using these techniques will allow the student to understand the drug discovery process, which includes a dialogue between crystallographers, medicinal chemists, biochemists, and biologists. 3 sh.

Prerequisites: CHEM 370 or instructor's permission.

CHEM582: Biochemical Pharmacology (3 hours lecture)

How drugs interact with, and influence biochemical pathways relevant to disease in the whole organism. Topics covered in this course deal with a review of fundamental concepts in biochemistry relevant to drug discovery, the process of drug discovery and specific examples of drug interactions with biochemical pathways and how they impact human disease. 3 sh.

Prerequisites: CHEM 370 and CHEM 371.

CHEM590: Selected Topics-Advanced Chemistry (3 hours lecture)

An in-depth study of selected areas in either analytical, inorganic, organic or physical chemistry, with special emphasis upon recent developments in the field. May be repeated three times for a maximum of 12 credits as long as the topic is different each time. 3 sh.

Prerequisites: CHEM 341 (Physical Chemistry II) or instructor's permission.

CHEM595: Graduate Research

Directed individual laboratory investigation under guidance of faculty advisor. May be elected once or twice, maximum credit allowed is 3 semester hours. 1 - 3 sh.

Prerequisites: Completion of 12 semester hours in this graduate program; instructor's permission.

CHEM599: Graduate Seminar (1 hour lecture)

An individual, non-experimental investigation and a formal presentation of scientific literature. 1 sh.

Prerequisites: CHEM 598.

MATH122: Calculus I (4 hours lecture)

Limits, continuity; derivative and differentiation; applications of the derivative, maxima, minima, and extreme considerations; antiderivatives; Riemann integral. 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Readiness Test.)

MATH221: Calculus II (4 hours lecture)

Riemann integral applications, transcendental functions, techniques of integration, improper integrals, L'Hospital's rule, infinite series. 4 sh.

Prerequisites: MATH 122 with grade of C- or better.

PHYS191: University Physics I (3 hours lecture, 2 hours lab)

This one-semester calculus-based course including laboratory is a study of the principles of physics and some applications to society's problems. Topics covered include mechanics, thermodynamics, fluids, and harmonic motion. 4 sh.

Prerequisites: MATH 122 is prerequisite or co-requisite.

PHYS192: University Physics II (3 hours lecture, 2 hours lab)

Calculus-based course. Study of some principles of physics and some applications to society's problems. Topics include: wave motion, sound and noise pollution, optics, electricity, lasers, nuclear theory, radiation, nuclear reactors, waste disposal. 4 sh.

Prerequisites: MATH 221 is prerequisite or corequisite.

STAT330: Fundamentals of Modern Statistics I (3 hours lecture)

Displaying, describing and modeling data; arrangements for producing data; probability; methods for drawing conclusions from data: significance testing, confidence interval estimation, linear regression, analysis of variance. Examples from many disciplines including the social and natural sciences. Statistical software is used. 3 sh.

Prerequisites: MATH 221 with a grade of C- or better.

STAT401: Applied Statistics for the Sciences (3 hours lecture)

Organizing, displaying, and describing data; designing experiments; methods for drawing conclusions from data; significance testing, confidence intervals, linear regression, analysis of variance, chi-square tests of independence. Examples from disciplines in the natural and physical sciences. Statistical software is used. Not for Mathematics and Computer Science majors. 3 sh.

Prerequisites: MATH 111 or Math 112.