Science Informatics Major (B.S.) - 2015 University Catalog


SCIENCE INFORMATICS MAJOR

Complete 79 semester hours including the following 2 requirement(s):

  1. SCIENCE INFORMATICS MAJOR REQUIREMENTS

    Complete the following 5 requirement(s) for 53 semester hours:

    1. SCIENCE INFORMATICS COURSES

      Complete the following 2 courses:

      SCIF 110 Introduction to Science Informatics (3 hours lecture) 3
      SCIF 497 Research Experience in Science Informatics I (3 hours lecture) 3
    2. BIOLOGY/MOLECULAR BIOLOGY REQUIREMENTS

      Complete the following 2 requirements:

      1. Complete 2 courses:

        BIOL 230 Cell and Molecular Biology (3 hours lecture, 3 hours lab) 4
        BIOL 380 Genetics (3 hours lecture, 3 hours lab) 4
      2. Complete 1 course from the following:

        BIOL 487 Statistical Genomics (3 hours lecture) 3
        STAT 487 Statistical Genomics (3 hours lecture) 3
    3. CHEMISTRY/BIOCHEMISTRY REQUIREMENTS

      Complete the following 3 courses:

      CHEM 120 General Chemistry I (3 hours lecture, 3 hours lab) 4
      CHEM 121 General Chemistry II (3 hours lecture, 3 hours lab) 4
      CHEM 230 Organic Chemistry I (3 hours lecture) 3
    4. COMPUTER SCIENCE REQUIREMENTS

      Complete the following 5 courses:

      CSIT 111 Fundamentals of Programming I (3 hours lecture) 3
      CSIT 112 Fundamentals of Programming II (3 hours lecture) 3
      CSIT 212 Data Structures and Algorithms (3 hours lecture) 3
      CSIT 337 Internet Computing (May be either 3 hours of lecture or 3 hours of seminar) 3
      CSIT 355 Database Systems (3 hours lecture) 3
    5. MATHEMATICS REQUIREMENTS

      Complete the following 2 requirements:

      1. Complete 2 courses:

        CSIT 270 Discrete Mathematics (3 hours lecture) 3
        STAT 401 Applied Statistics for the Sciences (3 hours lecture) 3
      2. Complete 1 course from the following:

        MATH 116 Calculus A (4 hours lecture) 4
        MATH 122 Calculus I (4 hours lecture) 4
  2. TRACKS & ELECTIVES

    Complete 1 of the following tracks for a total of 26 semester hours:

    1. COMPUTER SCIENCE TRACK

      Complete 2 requirements:

      1. Complete 2 courses for 6 semester hours:

        CSIT 315 Software Engineering I (3 hours lecture) 3
        CSIT 415 Software Engineering II (3 hours lecture) 3
      2. Complete 20 semester hours from the following:

        BIOL 435 Experimental Molecular Biology (6 hours lab) 3
        BIOL 457 Virology (3 hours lecture) 3
        BIOL 458 Microbial Genetics (3 hours lecture) 3
        BIOL 497 Genomics (3 hours lecture) 3
        CHEM 370 Biochemistry I (3 hours lecture) 3
        CSIT 432 Systems Administration (3 hours lecture) 3
        CSIT 437 Web Services (3 hours lecture) 3
        CSIT 495 Topics in Computer Science for Undergraduates (3 hours lecture) 1-3
        MATH 221 Calculus II (4 hours lecture) 4
        MATH 340 Probability (3 hours lecture) 3
        SCIF 391 Science Informatics Summer Internship 3
        SCIF 498 Research Experience in Science Informatics II (3 hours lecture) 3
    2. BIOINFORMATICS TRACK

      Complete 2 requirements:

      1. Complete 6 courses for 20 semester hours:

        BIOL 112 Principles of Biology I (3 hours lecture, 3 hours laboratory) 4
        BIOL 113 Principles of Biology II (3 hours lecture, 3 hours laboratory) 4
        BIOL 350 Microbiology (3 hours lecture, 3 hours lab) 4
        BIOL 434 Molecular Biology (3 hours lecture) 3
        CHEM 231 Organic Chemistry II (3 hours lecture) 3
        CHEM 370 Biochemistry I (3 hours lecture) 3
      2. Complete 6 semester hours from the following:

        BIOL 435 Experimental Molecular Biology (6 hours lab) 3
        BIOL 457 Virology (3 hours lecture) 3
        BIOL 458 Microbial Genetics (3 hours lecture) 3
        BIOL 497 Genomics (3 hours lecture) 3
        CSIT 315 Software Engineering I (3 hours lecture) 3
        CSIT 432 Systems Administration (3 hours lecture) 3
        CSIT 437 Web Services (3 hours lecture) 3
        CSIT 495 Topics in Computer Science for Undergraduates (3 hours lecture) 1-3
        MATH 221 Calculus II (4 hours lecture) 4
        MATH 340 Probability (3 hours lecture) 3
        SCIF 391 Science Informatics Summer Internship 3
        SCIF 498 Research Experience in Science Informatics II (3 hours lecture) 3
    3. CHEMINFORMATICS TRACK

      Complete 2 requirements:

      1. Complete 6 courses for 18 semester hours:

        BIOL 350 Microbiology (3 hours lecture, 3 hours lab) 4
        BIOL 434 Molecular Biology (3 hours lecture) 3
        CHEM 231 Organic Chemistry II (3 hours lecture) 3
        CHEM 232 Experimental Organic Chemistry I (4 hours lab) 2
        CHEM 370 Biochemistry I (3 hours lecture) 3
        CHEM 372 Experimental Biochemistry I (1 hour lecture, 3 hours lab) 2
      2. Complete 8 semester hours from the following:

        BIOL 435 Experimental Molecular Biology (6 hours lab) 3
        BIOL 457 Virology (3 hours lecture) 3
        BIOL 458 Microbial Genetics (3 hours lecture) 3
        BIOL 497 Genomics (3 hours lecture) 3
        CSIT 315 Software Engineering I (3 hours lecture) 3
        CSIT 432 Systems Administration (3 hours lecture) 3
        CSIT 437 Web Services (3 hours lecture) 3
        CSIT 495 Topics in Computer Science for Undergraduates (3 hours lecture) 1-3
        MATH 221 Calculus II (4 hours lecture) 4
        MATH 340 Probability (3 hours lecture) 3
        SCIF 391 Science Informatics Summer Internship 3
        SCIF 498 Research Experience in Science Informatics II (3 hours lecture) 3

Course Descriptions:

BIOL112: Principles of Biology I (3 hours lecture, 3 hours laboratory)

Principles of Biology I involves the study of life from molecule to multicellular organism with focus on structure and function of cells, mechanisms of heredity and change, and the ways in which these processes shape higher levels of biological organization. This course is designed to fulfill the first core course requirement of the biology major. 4 sh.

Prerequisites: MATH 100 with a grade of C- or higher or a satisfactory score on the Math department's precalculus readiness test.

BIOL113: Principles of Biology II (3 hours lecture, 3 hours laboratory)

Principles of Biology II will provide an introductory level study of biodiversity and the origins of life, phylogenetic relationships among organisms, genetics, developmental biology, reproduction, the biology of populations and communities, and ecosystem processes. 4 sh.

Prerequisites: MATH 100 with a grade of C- or higher or a satisfactory score on the Math department's precalculus readiness test.

BIOL230: Cell and Molecular Biology (3 hours lecture, 3 hours lab)

An introduction to the chemistry, structure, and function of prokaryotic and eukaryotic cells. Topics covered include membrane structure and transport processes, bioenergetics and energy transformations in cells, DNA replication and expression, protein synthesis, and cell movement. 4 sh.

Prerequisites: CHEM 120 with a grade of "C-" or better.

BIOL350: Microbiology (3 hours lecture, 3 hours lab)

A study of bacteria, yeast, molds and other microorganisms in relation to modern biological concepts and the welfare of man. Standard techniques employed in the laboratory. 4 sh.

Prerequisites: BIOL 230 with a grade of C- or higher and CHEM 120 with a grade of C- or higher.

BIOL380: Genetics (3 hours lecture, 3 hours lab)

Lecture and lab. Heredity, gene and chromosomal structure and function, gene regulation, mutation and repair, genes in populations, genetic manipulation, and applied genetics are covered. Lab exercises demonstrate genetic concepts. A semester-long project with research paper is required. Required of all biology majors and minors. Meets the University Writing Requirement for majors in Biology, Molecular Biology and Science Informatics. 4 sh.

Prerequisites: BIOL 230 with a grade of C- or higher and CHEM 120 with a grade of C- or higher.

BIOL434: Molecular Biology (3 hours lecture)

This course is designed to examine the molecular biology of plant and animal cells. 3 sh.

Prerequisites: BIOL 350 with a grade of C- or higher and BIOL 380 with a grade of C- or higher and CHEM 370 with a grade of C- or higher.

BIOL435: Experimental Molecular Biology (6 hours lab)

A laboratory course that will introduce biology and molecular biology majors to the basic techniques of modern molecular biology. Techniques to be covered include nucleic acid isolation, restriction enzyme mapping, plasmid manipulation and subcloning, genomic library construction, PCR amplification, and DNA sequence analysis. 3 sh.

Prerequisites: BIOL 434 with a grade of C- or higher.

BIOL457: Virology (3 hours lecture)

This course will develop the fundamental principles of modern virology and examine the connection between viruses and disease. It will examine the molecular biology of virus replication, infection, gene expression, the structure of virus particles and genomes, pathogenesis, and classification of viruses. 3 sh.

Prerequisites: BIOL 380 with a grade of C- or better.

BIOL458: Microbial Genetics (3 hours lecture)

Microbial Genetics provides students with an understanding of the basis for genetic processes in microorganisms and the implication for higher organisms. The focus of the course will be on prokaryotes, particularily E.coli, and viruses, primarily bacteriophages. Current developments in microbial genetics, such as bioinformatics and genomics, will be presented. 3 sh.

Prerequisites: BIOL 350 with a grade of C- or higher and BIOL 380 with a grade of C- or higher.

BIOL487: Statistical Genomics (3 hours lecture)

Analysis of discrete data illustrated with genetic data on morphological characters, allozymes, restriction fragment length polymorphisms and DNA sequences. Maximum likelihood and Bayesian estimation including iterative procedures. Numerical resampling and bootstrapping. Development of statistical techniques for characterizing genetic disequilibrium and diversity. Locating genes with markers. Cross listed with Mathematical Sciences STAT 487. 3 sh.

Prerequisites: BIOL 380 with a grade of C- or higher; and STAT 401 with a grade of C- or higher or STAT 440 with a grade of C- or higher.

BIOL497: Genomics (3 hours lecture)

The course will examine the associations among nucleic acid sequence (RNA and DNA), structure, and function in complex biological systems, while treating these systems as biological databases. Both computer program-based and laboratory methods will be discussed to better understand the relationship between nucleic acid sequence and function. Future opportunities and current limitations of genome analyses will be critically addressed. 3 sh.

Prerequisites: BIOL 230 with a grade of C- or higher and BIOL 380 with a grade of C- or higher.

CHEM120: General Chemistry I (3 hours lecture, 3 hours lab)

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to atomic and molecular structure, bonding, stoichiometry, states of matter, solutions, and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. 4 sh.

Prerequisites: Satisfactory score on the Mathematics readiness test OR a grade of C- or better in MATH 100 or MATH 111 or MATH 112 or MATH 116 or MATH 122 or MATH 221 or MATH 222 OR concurrent enrollment in MATH 100. Satisfactory score on the Chemistry readiness test OR a grade of C- or better in CHEM 105 or CHEM 106.

CHEM121: General Chemistry II (3 hours lecture, 3 hours lab)

Introductory lecture and laboratory course for science majors, prerequisite for all advanced chemistry courses. Introduction to thermochemistry, kinetics; general acid base, precipitation, redox equilibria, electrochemistry and selected topics in descriptive inorganic chemistry. Laboratory stresses techniques and data treatment and their use in examining chemical systems. 4 sh.

Prerequisites: CHEM 120 with a grade of C- or better.

CHEM230: Organic Chemistry I (3 hours lecture)

Structure and bonding in organic compounds: nomenclature, reactions, properties, and aromatic compounds: stereochemistry; structure analysis by IR, NMR, UV, and MS; introduction to molecular orbital theory. 3 sh.

Prerequisites: CHEM 121 with a grade of C- or better.

CHEM231: Organic Chemistry II (3 hours lecture)

Nomenclature, reactions, properties, and synthesis of ethers, epoxides, alcohols, amines, and carbonyl compounds; carbohydrates; amino acids, peptides and proteins; pericyclic reactions; synthetic polymers. 3 sh.

Prerequisites: CHEM 230 with a grade of C- or better.

CHEM232: Experimental Organic Chemistry I (4 hours lab)

A laboratory course to be taken concurrently with CHEM 230. Basic techniques for the separation, analysis and synthesis of organic compounds: recrystallization, distillation, extraction, GC, HPLC, TLC, GC/MS, IR, H/C13- NMR, chemical safety methods and regulations. 2 sh.

Prerequisites: CHEM 230 is a prerequisite or corequisite.

CHEM370: Biochemistry I (3 hours lecture)

Organization of the living cell; structure, function and chemistry of proteins, carbohydrates and lipids; bioenergetics and oxidation. 3 sh.

Prerequisites: CHEM 231 with a grade of C- or better.

CHEM372: Experimental Biochemistry I (1 hour lecture, 3 hours lab)

A lecture and laboratory course of experimental methods in biochemistry. Biochemical applications of spectroscopy, chromatographic methods, enzyme kinetics, DNA and protein purification and electrophoretic techniques. 2 sh.

Prerequisites: CHEM 231 and CHEM 232 with a grade of C- or better in both courses. CHEM 370 may be taken as a prerequisite or corequisite.

CSIT111: Fundamentals of Programming I (3 hours lecture)

Basic theory of digital computers. Syntax and semantics of a programming language. Algorithms: logic, design, testing and documentation. Previous course CMPT 183 effective through Spring 2014. 3 sh.

Prerequisites: MATH 100. MATH 112 may be taken as a corequisite or prerequisite.

CSIT112: Fundamentals of Programming II (3 hours lecture)

Continuation of CSIT 111. Algorithm development involving user functions; subroutines, recursions, structures file manipulation. Previous course CMPT 184 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 111, CSIT 104 and MATH 112.

CSIT212: Data Structures and Algorithms (3 hours lecture)

Creation and manipulation of in-memory data structures including graphs, lists, queues, sets, stacks and trees; searching, sorting and other algorithms for in-memory data structures. Meets the University Writing Requirement for majors in Computer Science and Science Informatics. Previous course CMPT 287 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 112.

CSIT270: Discrete Mathematics (3 hours lecture)

The structures include sets, graphs, digraphs, trees, networks, lattices, matrices, semigroups and groups. Many practical business and scientific problems can be posed and solved by the use of these structures. Previous course CMPT 285 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 111.

CSIT315: Software Engineering I (3 hours lecture)

Utilization of software engineering principles and techniques for the specification, analysis, and design of high-quality complex software systems including both technical and non-technical aspects. Previous course CMPT 371 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 212 and CSIT 230.

CSIT337: Internet Computing (May be either 3 hours of lecture or 3 hours of seminar)

This course discusses and investigates the current web tools and technologies that are used in web site design. Focus will be on the markup languages of XHTML and XML; Dynamic HTML; Client side programming language JavaScript; Server side programming, Servlets, JavaServer pages and ASP. Previous course CMPT 250 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 112 and CSIT 230.

CSIT355: Database Systems (3 hours lecture)

A comprehensive collection of database organizations and design tools: file organizations and evaluations, database structures, schemata and implementations. Database security, operations and management. Previous course CMPT 483 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 212 and CSIT 230 and CSIT 270.

CSIT415: Software Engineering II (3 hours lecture)

This course utilizes software engineering principles and techniques for the implementation, testing and maintenance of high-quality complex software systems, as designed in a previous course (CMPT 315). Previous course CMPT 372 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 315.

CSIT432: Systems Administration (3 hours lecture)

The administration and management of Linux Computer Systems. Includes installation; user/process management; configuration of services and device handling; introduction to C; (i) syntax of functions and basic structure, keywords, expressions, variables, scoping and lifetime, types, and type conversion, arrays and pointers, run-time stack, function invocation, parameter passing, passing arrays, memory & segments (dynamic, static, automatic), dynamic allocation, (ii) compilation process; preprocessor, compiling object code, static and dynamic linking; file I/0, Streams, Reading and Writing files, command line options, combining using pipes and I/0 redirection, (iii) Profiling tools (Gprof), Binary Tools (LD, LDD, NM), Debugging (GDB, DDD); Basic Shell scripting, (iv) Build Tools (Make). Previous course CSIT 420 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 340.

CSIT437: Web Services (3 hours lecture)

Distributed Information Systems and Middleware Enterprise Application Integration and web technologies, web services and related technologies, real-world examples REST architectural style, Web 2.0, coordination and composition. Previous course CSIT 470 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 337.

CSIT495: Topics in Computer Science for Undergraduates (3 hours lecture)

Study of specialized topics in computer science. May be repeated once for a maximum of 6.0 credits as long as the topic is different. Previous course CMPT 495 effective through Spring 2014. 1 - 3 sh.

Prerequisites: CSIT 313 or CSIT 335 or CSIT 337 or CSIT 340 or CSIT 345 or CSIT 355 or CSIT 357 or CSIT 379.

MATH116: Calculus A (4 hours lecture)

Differentiation and integration of functions, including trigonometric functions. Applications to biology and geoscience. 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Readiness Test.)

MATH122: Calculus I (4 hours lecture)

Limits, continuity; derivative and differentiation; applications of the derivative, maxima, minima, and extreme considerations; antiderivatives; Riemann integral. 4 sh.

Prerequisites: MATH 111 or MATH 112 or placement through the Montclair State University Placement Test (MSUPT) or a satisfactory score on department's Calculus Readiness Test. (Students who did not satisfy the course prerequisite at MSU and students who received a grade of D-, D, or D+ in the prerequisite course taken at MSU are required to demonstrate competency on the department's Calculus Readiness Test.)

MATH221: Calculus II (4 hours lecture)

Riemann integral applications, transcendental functions, techniques of integration, improper integrals, L'Hospital's rule, infinite series. 4 sh.

Prerequisites: MATH 122 with grade of C- or better.

MATH340: Probability (3 hours lecture)

Chance and variability, elements of combinatorics, Bayes' theorem, random variables, binomial, poisson and normal distributions, applications to statistics. 3 sh.

Prerequisites: MATH 221 with a grade of C- or better.

SCIF110: Introduction to Science Informatics (3 hours lecture)

This course introduces students, including Science Informatics majors, to timely topics encompassed in the interdisciplinary field of science informatics. Students learn about genomics, drug discovery, geographic information systems and other science topics with a hands-on, ethics-focused case study approach. 3 sh.

SCIF391: Science Informatics Summer Internship

During the summer under the guidance of a sponsor in a medical or industrial site outside of the University, students will investigate advanced, individual research problems appropriate to science informatics. Although students are strongly encouraged to enroll in an off-campus externship, an equivalent on-campus experience with the Biology and Molecular Biology, Chemistry and Biochemistry, Computer Science or Mathematical Sciences department will be accepted for credit. Previous course SCIF 350 effective through Spring 2014. 3 sh.

Prerequisites: CSIT 212 and CSIT 270 and CSIT 337 and BIOL 434.

SCIF497: Research Experience in Science Informatics I (3 hours lecture)

The student works as a member of an interdisciplinary Science Informatics student team and develops a research proposal to a science informatics problem posed by Montclair State faculty, other academic institutions, or industry representatives. Previous course SCIF 491 effective through Spring 2014. 3 sh.

Prerequisites: SCIF 391 and departmental approval.

SCIF498: Research Experience in Science Informatics II (3 hours lecture)

The student works as a member of an interdisciplinary Science Informatics student team and implements his/her research proposal developed in SCIF 497 for a science informatics problem posed by Montclair State faculty, other academic institutions, or industry representatives. Previous course SCIF 492 effective through Spring 2014. 3 sh.

Prerequisites: SCIF 497 and departmental approval.

STAT401: Applied Statistics for the Sciences (3 hours lecture)

Organizing, displaying, and describing data; designing experiments; methods for drawing conclusions from data; significance testing, confidence intervals, linear regression, analysis of variance, chi-square tests of independence. Examples from disciplines in the natural and physical sciences. Statistical software is used. Not for Mathematics and Computer Science majors. 3 sh.

Prerequisites: MATH 111 or Math 112.

STAT487: Statistical Genomics (3 hours lecture)

Analysis of discrete data illustrated with genetic data on morphological characters, allozymes, restriction fragment length polymorphisms and DNA sequences. Maximum likelihood and Bayesian estimation including iterative procedures. Numerical resampling and bootstrapping. Development of statistical techniques for characterizing genetic disequilibrium and diversity. Locating genes with markers. Cross listed with Biology and Molecular Biology BIOL 487. 3 sh.

Prerequisites: BIOL 380 and STAT 330 or STAT 401, or equivalent.