Molecular Biology (M.S.) - Graduate - 2009 University Catalog

You are viewing the 2009 University Catalog. Please see the newest version of the University Catalog for the most current version of this program's requirements.


 


MOLECULAR BIOLOGY

Complete 32 semester hours including the following 3 requirement(s):

  1. CORE COURSES

    Complete 4 courses for 11 semester hours:

    BIOL 547 Molecular Biology I 3
    BIOL 548 Molecular Biology II 4
    BIOL 556 Molecular Biology of Proteins 3
    BIOL 592 Graduate Colloquium 1
  2. RESEARCH IN BIOLOGICAL LITERATURE

    Complete for 1 semester hours.

    BIOL 597 Research in Biological Literature 1
  3. ELECTIVES & CULMINATING ACTIVITY

    Complete the following 2 requirement(s) for a total of 20 semester hours:

    1. CONCENTRATION/SPECIALIZATION COURSES

      Complete 14 semester hours-16 semester hours from the following list

      BIOL 512 Topics in Modern Genetics 3
      BIOL 513 Instrumentation and Techniques for Biological Science 4
      BIOL 520 Plant Physiology 3
      BIOL 522 Plant Pathology 3
      BIOL 531 Medical Parasitology 3
      BIOL 533 Advanced Cell Biology 3
      BIOL 540 Mammalian Physiology 3
      BIOL 542 Advanced Endocrinology 3
      BIOL 543 Advances in Immunology 3
      BIOL 545 Experimental Endocrinology 4
      BIOL 549 Topics in Developmental Biology 3
      BIOL 550 Topics in Microbiology 3
      BIOL 551 Intermediary Metabolism I 3
      BIOL 552 Biology of Lipids 3
      BIOL 554 Microbial Physiology 3
      BIOL 555 Medical Genetics 3
      BIOL 557 Virology 3
      BIOL 558 Microbial Genetics 3
      BIOL 560 Molecular Genetics 3
      BIOL 571 Physiological Plant Ecology 4
      BIOL 579 Physiological Ecology of Animals 3
      BIOL 580 Evolutionary Mechanisms 3
      BIOL 593 Molecular Ecology 3
      BIOL 594 Signal Transduction 3
      BIOL 598 Selected Techniques in Molecular Biology 1.5
      CHEM 570 Selected Topics in Advanced Biochemistry 3
    2. CULMINATING ACTIVITY

      Complete 1 of the following options:

      1. THESIS

        1. Complete for 6 semester hours.

          BIOL 698 Master's Thesis 4-6
        2. Submit the completed Thesis original and one copy to the Graduate Office. See Thesis Guidelines for details.

      2. NON-THESIS RESEARCH OPTION

        Complete for 4 semester hours.

        BIOL 599 Introduction to Biological Research 4

Course Descriptions:

BIOL512: Topics in Modern Genetics

Seminar course. Selected topics from current development in genetic research, including chromosome and gene fine structure, extra chromosomal genetic elements, genetic engineering, and aspects of biomedical genetic research. May be repeated once for a maximum of 6.0 credits as long as the topic is different. 3 sh.

Prerequisites: Undergraduate course in genetics.

BIOL513: Instrumentation and Techniques for Biological Science

This course is designed to acquaint students with modern analytical and research techniques in biology, including manometry, spectrophotometry, electrophoresis, chromatography, microbial batch growth and assay techniques, immunotechniques and evaluation of experimental design and data. 4 sh.

Prerequisites: 24 semester hours in biology.

BIOL520: Plant Physiology

Investigation of physiology of plants. Plant growth, development and reproduction as well as the new advances in plant physiology. Water relations of plants, mineral nutrition, physiological significance of soil and soil moisture, photosynthesis, respiration, plant biosynthesis and dynamics of growth. 3 sh.

Prerequisites: Permission of instructor.

BIOL522: Plant Pathology

Causes, symptoms, and control of plant diseases. 3 sh.

Prerequisites: Botany and microbiology.

BIOL531: Medical Parasitology

To study the phenomenon of parasitism as applied to man and his domestic animals. Areas of emphasis include specific adaptations for parasitism and transmission, effects on the host, epidemiology and control. 3 sh.

Prerequisites: Zoology.

BIOL533: Advanced Cell Biology

Detailed analysis of cellular structure and function. Topics to be covered include the role of subcellular organelles in maintaining cell viability, analysis of cytoskeletal components, structure and function of the plasma membrane and cellular defects that lead to cancer and other disease states. 3 sh.

Prerequisites: Matriculation in the biology master's program or permission of professor.

BIOL540: Mammalian Physiology

A broad survey of the physiology of mammalian systems aimed at graduate students who lack an upper-level background in physiology at the undergraduate level. The principles of homeostatis mechanisms as they apply to various organ systems will be stressed. 3 sh.

Prerequisites: Graduate standing, but not open to students who have completed undergraduate upper division Mammalian/Human Physiology classes.

BIOL542: Advanced Endocrinology

A study of the physiology of the mammalian endocrine system with emphasis on hormonal control of homeostasis. 3 sh.

Prerequisites: Endocrinology and cell biology.

BIOL543: Advances in Immunology

To study in detail selected topics in immunology. 3 sh.

Prerequisites: Immunology.

BIOL545: Experimental Endocrinology

A seminar and laboratory course in endocrinology in which the various endocrine glands will be surgically removed or chemically destroyed and the morphologic and physiologic effects measured and observed. 4 sh.

Prerequisites: Endocrinology.

BIOL547: Molecular Biology I

Central concepts at the cellular level will be emphasized. Contemporary viewpoints in the areas of biomolecules, energy yielding and energy requiring processes and transfer of genetic information. 3 sh.

Prerequisites: Cell biology, and one year organic chemistry.

BIOL548: Molecular Biology II

Central concepts at the cellular level will be emphasized. Contemporary viewpoints in the areas of biomolecules, energy yielding and energy requiring processes and transfer of genetic information. The laboratory will deal with up-to-date investigative procedures via selected experiments. 4 sh.

Prerequisites: BIOL 547.

BIOL549: Topics in Developmental Biology

Seminar in the regulation of developmental events, including both classical morphogenesis and recent advances using techniques of cell and molecular biology. May be repeated once for a maximum of 6.0 credits as long as the topic is different. 3 sh.

Prerequisites: Genetics and developmental embryology.

BIOL550: Topics in Microbiology

Coverage of selected topics such as the microbial genetics, antibiotic action, bacteriophage, virus, cancer and microbial metabolism. Emphasis will be placed on practical applications of modern research in specific areas. May be repeated once for a maximum of 6.0 credits as long as the topic is different. 3 sh.

Prerequisites: Microbiology.

BIOL551: Intermediary Metabolism I

Discussion of interrelationships of catabolic and anabolic paths. Primary emphasis is placed on the metabolism of nucleic acids, carbohydrates, and proteins. 3 sh.

Prerequisites: Biochemistry and cell biology.

BIOL552: Biology of Lipids

Biological cycles, unity and diversity in metabolic paths, metabolic evolution, metabolic control mechanisms and other special topics. Primary emphasis is placed on the metabolism of lipids. 3 sh.

Prerequisites: Cell biology and organic chemistry.

BIOL554: Microbial Physiology

A study of microorganisms in terms of their morphology and metabolism. The significance of metabolic diversity and secondary metabolic products of various microorganisms will be explored through lecture topics. The economic significance of microbial metabolism in relation to industry and pathogenic diseases will be emphasized. 3 sh.

Prerequisites: Microbiology.

BIOL555: Medical Genetics

A detailed study and analysis of human genetics, inborn genetic diseases, genomics, gene therapy, and the Human Genome Project. 3 sh.

Prerequisites: A genetics course or permission of instructor.

BIOL556: Molecular Biology of Proteins

Study of the molecular biology of biomolecules, including proteins. The course will examine how changes in the three dimensional structure of biomolecules affect their biological function. Protein engineering, enzyme catalysis, and site-directed mutagenesis will be discussed. 3 sh.

Prerequisites: Admission into the graduate biology program or permission of department.

BIOL557: Virology

This course will develop the fundamental principles of modern virology and examine the connection between viruses and disease. It will examine the molecular biology of virus replication, infection, gene expression, the structure of virus particles and genomes, pathogenesis, classification of viruses, and contemporary viral research. 3 sh.

Prerequisites: Satisfactory completion of a Cell & Molecular Biology course or permission of instructor.

BIOL558: Microbial Genetics

Microbial Genetics provides students with an understanding of the basis for genetic processes in microorganisms and the implication for higher organisms. The focus of the course will be on prokaryotes, particularily E.coli, and viruses, primarily bacteriophages. Current developments in microbial genetics, such as bioinformatics and genomics, will be presented. 3 sh.

Prerequisites: BIOL 350, Microbiology.

BIOL560: Molecular Genetics

A course that will focus on biological research problems that are being addressed in eucaryotic systems from a molecular genetics viewpoint. 3 sh.

Prerequisites: BIOL 547 with a grade of "B" or better.

BIOL571: Physiological Plant Ecology

The effects of soil, light, and water on plant growth, as well as, toxic effects of metals and salinity are measured using growth chamber and greenhouse facilities. 4 sh.

Prerequisites: Botany and one course in field biology.

BIOL579: Physiological Ecology of Animals

A variety of different animals, ranging from protists to mammals, will be examined and compared to demonstrate the physiological adaptations they have evolved to successfully survive and reproduce. 3 sh.

Prerequisites: Graduate standing in Biology or permission of instructor.

BIOL580: Evolutionary Mechanisms

This course will provide students the opportunity to read primary resource material and interpret the findings of the data. This course will also teach students how to read, critique and present scientific data to a peer group. Students will analyze, discuss and present primary research articles with respect to scientific content, accuracy of the data and significance of the experiments. 3 sh.

Prerequisites: Matriculation in the biology master's program or permission of the instructor.

BIOL592: Graduate Colloquium

Students in this course will read primary resource material and interpret the data. This course will also teach students how to read, critique and present scientific data to a peer group. Students will analyze, discuss and present primary research articles with respect to scientific content, accuracy of the data and significance of the experiments. 1 sh.

Prerequisites: Matriculation in the biology master's program or permission of the professor.

BIOL593: Molecular Ecology

Detailed survey of the application of molecular methods to address ecological, behavioral, and conservation questions. Topics to be covered include the principles of most common molecular techniques used in molecular ecology, and application of those molecular techniques to phylogeography, behavioral ecology, population genetics, conservation genetics, and adaptive variation. Students will develop and present independent research proposal. 3 sh.

Prerequisites: BIOL 547 or instructor's permission.

BIOL594: Signal Transduction

This course will cover various aspects of cellular signaling from the plasma membrane to the nucleus. Topics will include specific signal transduction systems, methods for studying these systems and the results of these signaling events on cell division, cell differentiation and cell function. 3 sh.

Prerequisites: BIOL 547 or permission of instructor.

BIOL597: Research in Biological Literature

To allow the student to investigate and evaluate a specific topic in biology under the supervision of a faculty member and to develop the student's skills in presenting current research in both the written and oral modes. 1 sh.

Prerequisites: Departmental approval.

BIOL598: Selected Techniques in Molecular Biology

A laboratory course that trains students in advanced techniques in molecular biology. Students will learn how to perform a specific technique as well as learning the theory behind the technique. May be repeated three times for a maximum of 6.0 credits. 1.5 sh.

Prerequisites: Undergraduate or graduate molecular biology courses or equivalent and permission of instructor.

BIOL599: Introduction to Biological Research

A research experience in which students will be exposed to current biologic techniques by working with scientific investigators in industry, or within the department. Students will work on projects involving research techniques, data collection and the analysis and interpretation of the data. 4 sh.

Prerequisites: Departmental approval.

BIOL698: Master's Thesis

Independent research project done under faculty advisement. Students must follow the MSU Thesis Guidelines, which may be obtained from the Graduate School. Students should take BIOL 699 if they don't complete BIOL 698 within the semester. 4 - 6 sh.

Prerequisites: Departmental approval.

CHEM570: Selected Topics in Advanced Biochemistry

A detailed treatment of selected topics in biochemistry. Special emphasis upon recent developments. Protein structure, enzymology, metabolism, nucleic acid chemistry are examples of topics. This course may be repeated for credit indefinitely as long as the topic is different each time. 3 sh.

Prerequisites: CHEM 370 or instructor's permission.